Chicken Alfredo Lasagna Rollups: Twist On A Classic Recipe

I love lasagna, but it can get old pretty quickly. These chicken alfredo lasagna rollups are a fun and delicious twist on a classic dish. Pasta dinner recipes are perfect for a weeknight meal or a special occasion. The creamy Alfredo sauce, cheesy filling, and tender chicken will satisfy the whole family. Remember to use freshly grated cheese! It melts better and tastes amazing.

chicken alfredo lasagna rollup being lifted out of pan.

Chicken Alfredo Lasagna Rollups

These cheesy, creamy chicken alfredo lasagna rollups are a fun twist on classic comfort food. Makes 12 servings.
Prep Time 40 minutes
Cook Time 35 minutes
Total Time 1 hour 15 minutes
Serving Size 12 servings

Ingredients 

Lasagna Rollups

  • 12 lasagna noodles (you will need 12 good noodles, but get extra in case some break while cooking)
  • 3 ½ cups Alfredo Sauce (see ingredients below)
  • 3 cups chicken (diced and cooked – rotisserie chicken works great)
  • 2 ¾ cups mozzarella cheese freshly grated divided
  • 1 cup ricotta cheese
  • ½ cup Parmesan cheese freshly grated
  • 2 tablespoons chopped fresh parsley divided
  • ¾ teaspoon garlic salt
  • ½ teaspoon dried oregano
  • ¼ teaspoon pepper

Alfredo Sauce

  • ¾ cup butter
  • 2 teaspoons freshly minced garlic
  • ½ teaspoon chicken bouillon base such as Better than Bouillon
  • 2 tablespoons all-purpose flour
  • ½ teaspoon salt
  • ½ teaspoon coarsely ground black pepper
  • 2 ½ cups heavy whipping cream
  • 1 ¼ cups chicken broth
  • 1 ¾ cups freshly grated parmesan cheese

Instructions 

  • Make alfredo sauce. In a 12-inch skillet or Dutch oven, melt ¾ cup butter on medium-low heat. Add the minced garlic and cook for one minute. Whisk in the bouillon and flour. Add ½ teaspoon of salt and pepper. Slowly add broth and cream, whisking to combine ingredients. Gradually whisk in the 1 ¾ cups Parmesan, adding a handful at a time once the Parmesan cheese is melted and cooked into sauce. Keep sauce on the lowest heat setting on the stove, whisking occasionally to keep the sauce combined. It will continue to thicken as it sits.
  • Preheat oven. Preheat the oven to 350 degrees Fahrenheit.
  • Cook and cool lasagna noodles. Bring a large pot of water to a boil and cook the lasagna noodles according to package directions. Carefully drain and use tongs to lay the lasagna noodles flat on baking sheets lined with parchment paper to cool. Choose the best 12 noodles for the rollups, discarding any extra that may have tears or not lie flat.
    cooked lasagna noodles laid out on parchment covered baking sheet.
  • Set aside some alfredo sauce. Remove 1 cup of alfredo sauce and set aside to cool for a few minutes while you make the filling.
  • Make filling. In a medium-sized bowl, combine chicken, 1 ¼ cups shredded mozzarella cheese, ricotta cheese, Parmesan cheese, 1 tablespoon parsley, garlic salt, oregano, and pepper. Add the cup of alfredo sauce that was set aside.
    chicken and cheese filling in bowl.
  • Line bottom of pan with sauce. Spread ½ cup of the Alfredo sauce from the skillet onto the bottom of a 9×13 pan.
  • Fill noodles. Spread ⅓ cup of the chicken mixture evenly over one noodle. Roll up the noodle and place the filled, rolled lasagna noodle in the prepared pan, seam side down. Repeat for each noodle, using ⅓ cup of mixture each time.
  • Cover noodles. Pour the remaining Alfredo sauce (about 2 cups) over the rollups and sprinkle with the remaining 1 ½ cups Mozzarella cheese (about 2 tablespoons over each rollup).
  • Bake. Cover lasagna with aluminum foil and bake for 20 minutes. Remove the foil and bake for 15 minutes longer. Place lasagna under the broiler for 2-3 minutes to brown the tops of the lasagna rolls if desired. Remove the lasagna from the oven and sprinkle with the remaining tablespoon of chopped fresh parsley. Let the lasagna sit for 5 minutes before serving.

Notes

  • Use freshly grated parmesan cheese and mozzarella cheese. Not only do they taste better, but they melt better. Packaged pre-shredded cheese contains additives and preservatives that prevent cheese from melting as well.
  • If the Alfredo sauce seems a little thin after adding all the parmesan cheese, allow it to continue to simmer for an additional 5-10 minutes, whisking occasionally, and it will thicken.
Calories: 745kcal | Carbohydrates: 30g | Protein: 25g | Fat: 58g | Saturated Fat: 34g | Polyunsaturated Fat: 5g | Monounsaturated Fat: 15g | Trans Fat: 0.5g | Cholesterol: 196mg | Sodium: 1466mg | Potassium: 239mg | Fiber: 1g | Sugar: 4g | Vitamin A: 1597IU | Vitamin C: 2mg | Calcium: 387mg | Iron: 1mg

My family goes crazy for these lasagna rollups! They’re cheesy and good; everyone always returns for seconds. It’s a recipe I keep in my back pocket, along with my crockpot cheesy chicken and broccoli recipe.

two lasagna rollups on plate.

Even your pickiest eaters will love these, thanks to all the cheese.

Lasagna Rollup Tips

  • Don’t overcook your noodles! Slightly undercook them, as they’ll continue to soften in the oven. Nobody likes mushy lasagna rollups.
  • Use a rimmed baking sheet to lay out your noodles. This helps contain the mess and keeps them from sticking together.
  • An assembly line makes filling easier. Have your filling, sauce, and noodles ready to go before you start assembling.  
  • Don’t overfill the noodles. It makes them harder to roll and can cause them to burst. A nice, even layer of filling is all you need.
  • Use a spoon to help spread the sauce in the pan and over the rollups. This gives you more control and helps prevent a messy kitchen.

Key Ingredients and Tools

The right tools and ingredients will make this recipe a breeze! Here are a few things to keep in mind:

lasagna rollup ingredients on counter.
  • Chicken bouillon base. You can usually find this near the other bouillon cubes and broth. It adds a richer, deeper flavor to the Alfredo sauce.
  • Freshly grated Parmesan cheese. It makes a difference in flavor and how smoothly the Alfredo sauce comes together. You’ll find it in the deli section of your grocery store.
  • Large pot. You’ll need this to cook the lasagna noodles. Make sure it’s big enough to hold plenty of water so the noodles have room to cook evenly.
  • Tongs. These are helpful for carefully handling the lasagna noodles when transferring them from the boiling water to the baking sheet.

Having these items ready to go will help you make the best chicken alfredo lasagna rollups ever!

Serving Suggestions

Serve these lasagna rollups with a simple green salad, garlic parmesan dinner rolls, and steamed broccoli.

Troubleshooting and Help

Can I use a different kind of cheese?

Absolutely! While freshly grated Parmesan and mozzarella are best for melting and flavor, you can use your favorite cheeses. Just keep in mind that pre-shredded cheese might not melt as smoothly. If you want something different, fontina, Gruyère, or a smoked mozzarella would be delicious!

What if my Alfredo sauce is too thick?

If your sauce seems a little thick, thin it out with some extra cream or chicken broth. Just add a tablespoon at a time until you reach the desired consistency. You can also thin it out a bit when you reheat it.

Can I add some vegetables to the filling?

That’s a great idea! Sautéed spinach, mushrooms, or bell peppers would all be delicious additions to the filling. You could even add some chopped broccoli or zucchini. Just make sure to cook the vegetables before adding them to the filling.

I only have dried herbs. Can I use those instead of fresh parsley?

No problem! You can use dried parsley. Remember that dried herbs are usually more potent than fresh, so you’ll want to use about half the amount. Start with a teaspoon of dried parsley and add more to taste.

I hope this recipe becomes a new family favorite! If you have any questions or need more tips, leave a comment below. I’m always happy to help!

Storing Leftovers

In the Fridge:

  • The lasagna rollups can be stored in the refrigerator for 3 days.
  • Place them in an airtight container or wrap them tightly in plastic wrap.
  • Reheat gently in the microwave or oven until they are heated through.

Freezing:

  • Place the lasagna rollups in an airtight container or wrap them tightly in plastic wrap and aluminum foil.
  • Freeze them for up to 1 month.
  • Thaw overnight in the refrigerator before reheating.
  • Reheat gently in the microwave or oven until they are heated through.

Do not refreeze the lasagna rollups after they have been thawed. They will not freeze well if they are not completely cooled before being frozen. Always follow leftover and food safety guidelines.

I hope you love these chicken alfredo lasagna rollups as much as my family and I do. They are a fun twist on classic lasagna. Plus, they are delicious and can please a crowd. This is a new family favorite, and I hope it becomes a favorite in your house, too.

baked lasagna rollups in baking dish with parsley sprinkled on top.
picture of smiling female

By Katie Shaw

Katie lives in Virginia with her husband, three daughters, a chocolate lab, and over thirty chickens. She loves creating simple tutorials for sourdough, bread, and soap. Her recipes, articles, and YouTube videos reach millions of people per year.

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